Synthesis and performance of experimental resin-based dental adhesives reinforced with functionalized graphene and hydroxyapatite fillers

• Nano-powders of functionalized graphene and hydroxyapatite were synthesized. Novel, non-toxic dental adhesives formulated. In-vitro performance under clinically relevant environmental conditions aging enables clinical use. Functionalized fillers are proposed as reinforcing particles in light-cured for applications. Silica-silver-graphene (SiO 2 -Ag-Gr), silver-doped (HA-Ag), silver doped (HA-Ag-Gr), regular silica ) inorganic powders, together with bis-GMA (2,2-bis[4-(2-hydroxy-3-methacryloxypropoxy) oligomers, main components the organic matrix, Light field transmission electron microscopy diffraction proved successful synthesis powders. The experimental showed a positive influence on local biocompatibility up to 6 months an in-vitro simulation aging. Bonding human dentin reveal particular fracture pattern preferential adhesion restorative material contrast gold standard adhesive used reference, which adheres preferentially tooth structure. Bond strength was slightly lower, initial bond reliability improved, morphology interaction structure similar reference. have demonstrated their potential use